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PRAME (ZR383)
PRAME (ZR383)
İncele
PRAME (ZR383)
Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation, and apoptosis. This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis.
STAINING PATTERN :
Nucleus, cytoplasm, cell surface, chromosome, Golgi apparatus
POSITIVE CONTROL :
Testis or melanoma
CLONE :
ZR383
VOLUME :
PL2032-R7 7 ML RTU 70 TEST
PL2032-R1 1 ML RTU 10 TEST
PL2032-1 1 ML 1/100 100 TEST
PL2032-0,1 0,1 ML 1/100 1000 TEST
DATASHEET
SDS
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