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Home » IHC Antibodies » BRAF (V600E) (PL-20)

BRAF (V600E) (PL-20)

BRAF (V600E) (PL-20)

The BRAF gene encodes a protein that is part of the RAS-RAFMEK-ERK signaling pathway, which regulates cell division and proliferation. The V600E mutation in the BRAF gene leads to the production of a constitutively active BRAF protein, resulting in uncontrolled cell growth and division. Identifying the presence of this mutation is crucial for diagnosing and guiding the treatment of certain cancers.
STAINING PATTERN : Cytoplasmic
POSITIVE CONTROL : melanoma with BRAF V600E mutation
CLONE : PL-20
VOLUME :
PL2035-R7         7 ML RTU 70 TEST
PL2035-R1         1 ML RTU 10 TEST
PL2035-1            1 ML 1/100 1000 TEST
PL2035-0,1      0,1 ML 1/100 100 TEST